Best MoCRA compliance software in 2026

MoCRA obligations — facility registration, product listing with ingredient disclosure, adequate safety substantiation, adverse event recordkeeping with serious events reported within 15 business days, fragrance allergen labelling and GMP — are mostly administrative, so the category splits between software that prepares the data and services that file on your behalf. Cosmetri is the clearest example of the second: its published US FDA services cover product listing, facility registration, US Agent and adverse event management with MedWatch 3500A output. Formulator Online and CM Studio+ screen US requirements as software. Federal coverage alone is a partial answer, because California (Prop 65, AB-2771) and Washington State (Toxic-Free Cosmetics Act) restrict ingredients further, and retailer clean standards restrict further still with no legal force at all.

MoCRA gave the FDA real authority over cosmetics for the first time in eighty years, and turned a set of voluntary practices into obligations: register the facility, list every product and its ingredients, hold adequate safety substantiation, keep adverse event records and report serious ones. Most of it is administrative rather than technical, which is why the category divides between software that helps you prepare and services that file on your behalf.

We make one of these. Tamats is on this list and is labelled as ours. Everything factual about another tool is read from that vendor's own published material, with the URL and the date we read it, and each entry says plainly when the other option is the better buy — including ours, which carries what it is not for.

The tools, at a glance

What actually separates them

Software or services?

Facility registration and product listing are filings. Some vendors sell the software to prepare them, some will act as your US Agent and file. Know which you are buying.

Safety substantiation is still a human

MoCRA requires adequate substantiation for safety. No tool provides it. What a tool can do is get the ingredient-level regulatory work done and cited before it reaches an assessor.

Adverse event handling

Serious adverse events must be reported within 15 business days and records kept. If that workflow matters to you, check for it explicitly rather than assuming it comes with compliance.

Does it cover the state layer too?

California Prop 65 and AB-2771 and Washington's Toxic-Free Cosmetics Act impose their own ingredient restrictions on top of federal law. Federal-only coverage is a partial answer for the US market.

The list

1. Cosmetri (Registrar Corp)

   Best for

   Buying the filing itself: their published US FDA services cover product listing, facility registration and US Agent, plus adverse event management with MedWatch 3500A output and label and ingredient review.

   Cosmetics PLM plus GMP software, sold alongside a regulatory services business — software and the humans who file, in one contract.

   • —Cosmetri Product Manager (PLM) covers formulation, compliance checks, testing, packaging and cost, and a handoff to production, and states a 40K+ safe ingredients/chemicals selector.
   • —Cosmetri GMP covers ISO 22716 workflows: internal audits, CAPA/SCAR, an EDMS with SOP templates, complaints and recalls, SUE/OOS, KPIs and equipment/locations.
   • —They state Cosmetri is “the only ISO/IEC 27001:2022 certified PLM software”.

   Read from www.registrarcorp.com on 2026-08-03Full comparisonCosmetri alternatives

2. Formulator Online

   Best for

   Small brands wanting built-in US (MoCRA) and EU (CosIng) checks with auto-generated allergen reports, at a published annual price.

   Affordable, published-price formulation software for indie makers and small brands — the practical alternative for a one-market launch.

   • —A cloud application combining research, formulation and business management, aimed at beginners learning formulation, experienced cosmetic chemists, and entrepreneurs or brand owners.
   • —Formulation features include automatic INCI generation, allergen alerts, and calculations to 0.00001% accuracy; labelling generates the ingredient list in descending order.
   • —Compliance features are stated as built-in EU (CosIng) and US (MoCRA) checks with auto-generated allergen reports described as ready for CPSR audits, and the site names EU, US FDA/CFR and California regulations.

   Read from formulator.online on 2026-08-03Full comparisonFormulator Online alternatives

3. CM Studio+

   Best for

   US screening as part of a broader EU/US/ASEAN compliance module, from a free base tier.

   A free-tier formulation platform bundled with an ingredient marketplace — the closest thing in the category to a zero-cost starting point.

   • —CM Studio+ combines formulation software, ingredient search, compliance tools and a marketplace in one system, sold to manufacturers, formulators and ingredient suppliers.
   • —Listed capabilities include AI-powered formula generation and evaluation, raw material search across 8,000+ ingredients with live pricing, regulatory compliance screening for EU, US and ASEAN, PLM features (versioning, batch tracking, QC workflows), direct purchasing with checkout, equipment maintenance and document management, and free data migration from competing platforms.
   • —On the free tier they state: “The base version is free, which is already more than anyone else in this space offers... Advanced capabilities are how we sustain the platform, and you only pay for what you choose to use.”

   Read from cmstudioplus.com on 2026-08-03Full comparisonCM Studio+ alternatives

4. spreadsheets and a regulatory consultant

   Best for

   A single product line where a consultant handles registration and listing once and the ongoing burden is genuinely small.

   The default stack for most indie and scaling brands: a formula workbook, a folder of PDFs, and a consultant on retainer or per project.

   Full comparison

5. Tamats — this is our product

   Best for

   The ingredient-level work upstream of the filing: US FD&C and MoCRA screening with California and Washington State handled as their own sub-markets, each finding carrying the rule it came from.

   Not for

   Facility registration, product listing, acting as US Agent, adverse event reporting, or providing safety substantiation. Those are filings and accountable roles — Cosmetri sells them, Tamats does not.

Questions buyers actually ask

What does MoCRA require cosmetic companies to do?

The Modernization of Cosmetics Regulation Act requires facility registration and renewal, product listing with ingredient disclosure, adequate substantiation of safety, adverse event recordkeeping with reporting of serious events, and compliance with fragrance allergen labelling and good manufacturing practice requirements as the FDA implements them. Most obligations fall on the responsible person named on the label.

Does MoCRA compliance software file with the FDA for me?

Only if it is a services business as well as a software one. Cosmetri publishes US FDA services covering product listing, facility registration and US Agent alongside its software. Pure software tools help you prepare the data and screen the formula; the submission stays yours.

Is US federal compliance enough to sell cosmetics in the US?

No. California's Proposition 65 and AB-2771 and Washington State's Toxic-Free Cosmetics Act restrict ingredients beyond federal law, and retailer clean standards restrict further still with no legal force at all. A tool that screens only federal MoCRA and FD&C requirements is giving you a partial answer for the US market.