ANVISA — RDC resolutions
ANVISA RDC nº 529/2021 (prohibited substances) and RDC nº 530/2021 (restricted substances) for personal hygiene products, cosmetics and perfumes — as amended (RDC 995/2025, RDC 1.029/2026, RDC 1.030/2026)
23 compiled entries · 12 banned · 2 restricted · 7 flagged · 2 review
| Ingredient | Status | Limit | Rule | Citation |
|---|---|---|---|---|
| isopropylparaben | Banned | — | Listed in the Annex (prohibited substances) of RDC no. 529/2021, which internalizes MERCOSUL/GMC Resolution no. 62/14 (amended by 37/20); one of the non-permitted parabens (only methyl-, ethyl-, propyl- and butylparaben plus their sodium/potassium/calcium salts remain allowed as preservatives under RDC 528/2021). | Source |
| isobutylparaben | Banned | — | Listed in the Annex (prohibited substances) of RDC no. 529/2021 (MERCOSUL/GMC 62/14). | Source |
| phenylparaben | Banned | — | Listed in the Annex (prohibited substances) of RDC no. 529/2021. | Source |
| benzylparaben | Banned | — | Listed in the Annex (prohibited substances) of RDC no. 529/2021. | Source |
| pentylparaben | Banned | — | Listed in the Annex (prohibited substances) of RDC no. 529/2021. | Source |
| quaternium-15 | Banned | — | Formaldehyde-releasing preservative on the Annex (prohibited substances) of RDC no. 529/2021; effective Aug 11, 2024 with a 36-month adaptation period, revision aligned with EU CLP Regulation (EC) 1272/2008 hazard classification. | Source |
| chloroacetamide | Banned | — | Preservative added to the Annex (prohibited substances) of RDC no. 529/2021; effective Aug 11, 2024, 36-month adaptation period. | Source |
| chlorophene | Banned | — | Antimicrobial/preservative added to the Annex (prohibited substances) of RDC no. 529/2021; effective Aug 11, 2024, 36-month adaptation period. | Source |
| diphenyl(2,4,6-trimethylbenzoyl) phosphine oxide (TPO) | Banned | — | CAS 75980-60-8, a UV-cure photoinitiator. Added to the Annex of RDC no. 529/2021 via the amending resolution (RDC no. 995/2025, 30/10/2025); ban effective Feb 1, 2026. | Source |
| n,n-dimethyl-p-toluidine (DMPT) | Banned | — | CAS 99-97-8. Added to the Annex of RDC no. 529/2021 via the amending resolution (RDC no. 995/2025, 30/10/2025); ban effective Feb 1, 2026. | Source |
| butylphenyl methylpropional (Lilial / BMHCA) | Banned | — | Fragrance allergen moved into the prohibited Annex of RDC no. 529/2021 by RDC no. 1.030/2026 (published 15 Jun 2026); products already registered get an extended 18-month adaptation window (vs. the standard 12 months for other changes in that resolution). | Source |
| hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC / Lyral) | Banned | — | Fragrance allergen moved into the prohibited Annex of RDC no. 529/2021 by RDC no. 1.030/2026 (published 15 Jun 2026); 18-month adaptation window for already-registered products. | Source |
| diboron trioxide (boric oxide) | Flagged | — | Named as one of the additions to the prohibited-substances Annex of RDC no. 529/2021 in ANVISA's draft/public consultation (CP no. 1.304/2024, comment window Jan 7-Mar 7, 2025) that fed into RDC no. 1.030/2026; this specific entry's presence in the final adopted RDC 1.030/2026 text was not independently re-verified in this pass (though a related search shows 'boron compounds' generally were adopted as banned in the final rule). | Source |
| boric acid, its salts and esters | Flagged | — | Reported as moved from the restricted-substances Annex (RDC 530/2021) to the prohibited-substances Annex (RDC 529/2021) via the draft that became RDC no. 1.030/2026; exact final wording not independently re-verified, though a related search confirms boric acid/borax/borates were adopted as prohibited in the final rule. | Source |
| polyurethane-18 | Flagged | — | Named as a proposed addition to the prohibited Annex of RDC no. 529/2021 in ANVISA public consultation CP no. 1.304/2024. | Source |
| polyurethane-19 | Flagged | — | Named as a proposed addition to the prohibited Annex of RDC no. 529/2021 in ANVISA public consultation CP no. 1.304/2024. | Source |
| dibutyltin hydrogen borate | Flagged | — | Named as a proposed addition to the prohibited Annex of RDC no. 529/2021 in ANVISA public consultation CP no. 1.304/2024. | Source |
| diaminotoluene | Flagged | — | Named as a proposed addition to the prohibited Annex of RDC no. 529/2021 in ANVISA public consultation CP no. 1.304/2024. | Source |
| benzophenone-4 | Flagged | — | UV filter named as one of the example substances proposed for addition to the prohibited Annex of RDC no. 529/2021 in ANVISA public consultation CP no. 1.304/2024; final adopted status not independently re-verified. | Source |
| mequinol | Review | — | Named among the substances ANVISA's draft (CP no. 1.304/2024) proposed to remove/exclude from the prohibited-substances Annex of RDC no. 529/2021 (i.e. potential de-listing, not an active ban) — confirmed present in the source article's exclusion list. | Source |
| hydroquinone | Review | — | Named among substances ANVISA's CP no. 1.304/2024 draft proposed to exclude from the prohibited Annex of RDC 529/2021; independently corroborated — a separate search on the final RDC 1.030/2026 confirms hydroquinone was in fact removed from the prohibited list (now subject to specific-use conditions instead). | Source |
| formaldehyde | Restricted | — | Regulated with a maximum-concentration limit under Annex I (restricted substances) of RDC no. 530/2021, now updated/replaced by RDC no. 1.029/2026 (internalizing MERCOSUL/GMC Resolution 06/25, confirmed as a real resolution establishing Brazil's restricted-substances list and revoking RDC 530/2021); the exact numeric % ceiling could not be independently confirmed from the primary annex table in this pass and is therefore omitted rather than guessed. | Source |
| resorcinol | Restricted | — | Regulated with a maximum-concentration limit under Annex I (restricted substances) of RDC no. 530/2021, now updated/replaced by RDC no. 1.029/2026; exact numeric % ceiling not independently confirmed in this pass. | Source |
2026-07-21 · Compiled from cited primary sources. Informational only — not legal advice.
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